Guidance: SCT screening: handbook for antenatal laboratories

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Nhs England

October 10

09:02 2024

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This is the fifth edition of the NHS sickle cell and thalassaemia (SCT) screening programme handbook for antenatal laboratories.

This handbook is for staff working in antenatal screening laboratories. It brings together in one publication the national guidelines, recommendations, standards and specifications for the NHS SCT screening programme that relate to the work performed by screening laboratories.

See SCT screening: handbook for newborn laboratories for policy and standards for SCT screening newborn laboratories.

This publication was previously published by Public Health England, which closed on 30 September 2021.

Published 24 November 2021
Last updated 10 October 2024 +show all updates

10 October 2024
Added clarification that publication was previously published by Public Health England. Removed screening helpdesk information.
25 September 2024
Updated the email address for the screening support service.
5 September 2022
Removal of minimum testing requirements table in section 1.14 of 'Interpretation and reporting of antenatal screening results' chapter.
12 April 2022
Addition of sub-section to Introduction chapter 'Education of laboratory screening staff'
8 April 2022
Governance, quality assurance and accreditation chapter amended to include information on different models of SCT screening delivery and level of UKAS assessment required.
17 March 2022
Addition of explanatory paragraphs at the start of the Recommended report formats section.
2 March 2022
Updated wording for section 1.1 'Referral of blood samples for DNA analysis' in Referral of antenatal samples for molecular analysis attachment.
24 November 2021
First published.

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