GovWire

The handbook sets out laboratory standards and guidelines for cystic fibrosis (CF) screening in newborn babies, covering:

• the CF screening protocol
• laboratory quality and performance
• pre-analytical factors
• the immunoreactive trypsinogen (IRT) assay
• genetic analysis
• reporting and communication of results
• programme monitoring and data collection
• the background to CF screening

The handbook also includes links to screening result template letters, follow up forms, and information for parents/carers.

This publication was previously published by Public Health England, which closed on 30 September 2021.